Speaker
Description
The research presented in this talk investigates the multiphysics modelling of the human eye through a set of dedicated, tissue-specific studies regarding cornea, iris, vitreous body, and retina. Each ocular component is analysed independently isolating its dominant physical mechanisms. The cornea is modelled as a layered, anisotropic soft tissue, with particular emphasis on stromal collagen architecture and its influence on nonlinear, hyperelastic mechanical behaviour under intraocular pressure and external loading. Microstructure-informed constitutive formulations are employed to connect collagen organisation to macroscopic stress and deformation. The iris is examined as an active elastic fiber reinforced structure, where geometry and material response govern pupil dynamics and anterior segment mechanics. The vitreous body is described as a poro-elastic medium, capturing its role in load transmission, damping, and mechanical interaction with surrounding tissues. The retina is modelled as a thin, layered structure, composed by structural element with distinct mechanical properties, focusing on deformation, stress localisation, and interaction with the vitreous under physiological and pathological conditions. All together, these separated yet conceptually aligned studies define a coherent multiphysics perspective on ocular mechanics. The proposed modelling framework provides tissue-specific insight and lays the groundwork for future integrated simulations, disease modelling, and clinically oriented applications.