GIMC SIMAI Young 2026

Session

MS18 - Modeling of Elastic Multiphase Structures for Bio-Mechanics

5 Jun 2026, 09:00

Pisa

45. A geometric surface PDE model for cell–nucleus translocation through confinement

Francesca Ballatore (Université Côte d'Azur)

05/06/2026, 09:00

MS18 - Modeling of Elastic Multiphase Structures for Bio-Mechanics

Understanding how cells migrate through confined environments is crucial for elucidating fundamental biological processes, including cancer invasion, immune surveillance, and tissue morphogenesis. The nucleus, as the largest and stiffest cellular organelle, often limits cellular deformability, making it a key factor in navigating narrow pores or highly constrained spaces.

In this talk, I...

107. The role of remodeling and of the interstitial fluid in the description of “boundary effects” in multicellular aggregates

Andrea Pastore (Politecnico di Torino)

05/06/2026, 09:15

MS18 - Modeling of Elastic Multiphase Structures for Bio-Mechanics

Multicellular aggregates represent a wide class of hydrated soft biological media, in which the interplay between the flow of the interstitial fluid and the reorganization of the internal structure (remodeling) dictate the overall mechanical and hydraulic properties of the aggregates [1].

An interesting phenomenon occurring, for instance, when indentation and torsion tests are performed on...

148. Stretch Reversal under Biaxial Loading in Fibre-Reinforced Soft Tissues

Giulio Lucci (Sapienza University of Rome)

05/06/2026, 09:30

MS18 - Modeling of Elastic Multiphase Structures for Bio-Mechanics

When fibre-reinforced soft biological tissues undergo biaxial tension, it is generally assumed that both in-plane stretches will increase monotonically with the applied stress. However, under specific combinations of fibre architecture and loading biaxiality, a counterintuitive kinematic phenomenon of stretch reversal may occur, where one principal stretch reaches a local maximum and...

153. Swelling phenomena in the vitreous body

Alessandro Giammarini (Politecnico di Milano)

05/06/2026, 09:45

MS18 - Modeling of Elastic Multiphase Structures for Bio-Mechanics

The vitreous body is a transparent, highly hydrated tissue of spherical shape that is located between the lens and the retina in the ocular apparatus. In healthy conditions, the vitreous fills the ocular cavity and acts as a mechanical damper for the fluid’s motions in response to the saccadic eye movements [1]. The aging process, however, can impact negatively its biological functionality,...

119. Periodic beading in damaged axons: the role of surface elasticity

Francesco Magni (International School for Advanced Studies (SISSA))

05/06/2026, 10:00

MS18 - Modeling of Elastic Multiphase Structures for Bio-Mechanics

The Plateau--Rayleigh instability shows that a cylindrical fluid flow can be destabilized by surface tension. Similarly, capillary forces can make an elastic cylinder unstable when the elastocapillary length is comparable to the cylinder's radius. This is the case of axons: in the presence of several neurological pathologies, such as multiple sclerosis, Alzheimer's, and Parkinson's diseases,...